A LITTLE LIGHTBULB MOMENT
Drugs · Bone health
alendronate: bisphosphonate
Sign in to bookmark this concept and add private notes →
ALENDRONATE stands tall for thirty.
The idea behind the cue
Osteoporosis in appropriate patients. Inhibits osteoclast-mediated bone resorption. Key safety: Esophageal injury; hypocalcemia and other patient-specific contraindications. Monitor: Administration technique, calcium status and renal suitability. Counseling: Take with plain water on waking; remain upright at least 30 minutes and until after first food.
Practice this flashcard →Make it memorable
Short & simple
ALENDRONATE stands tall for thirty.
Acronym
ALENDRONATE stands tall for thirty.
Story
Osteoporosis in appropriate patients. Inhibits osteoclast-mediated bone resorption. Key safety: Esophageal injury; hypocalcemia and other patient-specific contraindications. Monitor: Administration technique, calcium status and renal suitability. Counseling: Take with plain water on waking; remain upright at least 30 minutes and until after first food.
Connect the pieces
- Role: Osteoporosis in appropriate patients
- Mechanism: Inhibits osteoclast-mediated bone resorption
- Safety: Esophageal injury; hypocalcemia and other patient-specific contraindications
- Monitor: Administration technique, calcium status and renal suitability
- Counseling: Take with plain water on waking; remain upright at least 30 minutes and until after first food
Know the limits
A focused drug study point, not a complete dosing or prescribing reference. Check indication, formulation, patient factors and the linked label.
DailyMed: FOSAMAX (ALENDRONATE SODIUM) TABLET [ORGANON LLC] ↗Check your understanding
A patient takes alendronate at bedtime then lies down. What change is needed?
A. Take together with calcium and antacids before breakfast.
B. Use the labeled morning, plain-water and upright administration instructions.
C. Take with milk to improve both absorption and calcium intake.
D. Take at bedtime with plain water but lie down immediately.
Reveal explanation
Use the labeled morning, plain-water and upright administration instructions.
Proper administration reduces esophageal exposure and supports absorption; bedtime dosing followed by lying down is inappropriate.