A LITTLE LIGHTBULB MOMENT
Pharmaceutical calculations and dimensional analysis · Applied dosing calculations
Indexed eGFR versus individual mL/min
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Take off the 1.73-size jacket when the task needs absolute flow.
The idea behind the cue
For relevant dosing decisions, an indexed eGFR can be converted to mL/min by multiplying by BSA/1.73; apply the drug-specific recommendation and clinical context.
Practice this flashcard →Make it memorable
Short & simple
Take off the 1.73-size jacket when the task needs absolute flow.
Acronym
Take off the 1.73-size jacket when the task needs absolute flow.
Story
Take off the 1.73-size jacket when the task needs absolute flow.
Connect the pieces
- 52 × 2.10/1.73 = 63.12 mL/min, rounded to 63. This conversion alone does not select a drug dose or make eGFR identical to creatinine clearance.
Know the limits
Original educational exercise. Use only the stated assumptions; a calculated quantity is not a prescribing recommendation. Real dosing requires drug-, indication- and patient-specific guidance.
NIDDK · Determining Drug Dosing in Adults with Chronic Kidney Disease ↗Check your understanding
An exercise supplies eGFR 52 mL/min/1.73 m2 and BSA 2.10 m2. Calculate the nonindexed estimate in mL/min, rounded to the nearest whole number. Enter the number only.
Reveal explanation
63 mL/min (tolerance ±0)
52 × 2.10/1.73 = 63.12 mL/min, rounded to 63. This conversion alone does not select a drug dose or make eGFR identical to creatinine clearance.
NIDDK · Determining Drug Dosing in Adults with Chronic Kidney Disease ↗